"We offer our condolences to all the families and friends who have lost love ones," Dr. Geoff Tunnicliffe, Secretary General of the WEA, said in a statement.
"I am calling on our global family to pray for those who have lost family or friends as a result of the tragedy," Dr. Tunnicliff said.
Though the exact motive behind the downing of the flight is yet to be confirmed, suspicions are that the hostile act was committed by people engaged in the ongoing conflict in the region.
"If this proves to be accurate, the WEA strongly condemns such violent action against innocent civilians who have no involvement in the conflict whatsoever."
Flight MH17 was reportedly en route from Amsterdam to Kuala Lumpur while it was shot down.
According to Dutch authorities, 27 Australians were on board the Boeing 777.
The global ministry, which has a network of churches across 129 countries, also renewed their call for prayers for reconciliation amidst the ongoing violence in the Ukrainian region.
"This situation is a reminder that we all must work together to promote a peaceful approach to resolving conflict no matter how complicated," Dr. Tunnicliff said.