The decision is supported by the 19 editors of Vogue magazines worldwide.
It could be the start of a major shift in the fashion industry, which has come under scrutiny in recent years over the health of size-zero models and their influence on young girls and women.
The 'health pact' was published in the June editions of the magazine and states that the editors will not use models under the age of 16 or those they believe to have an eating disorder.
The initiative is intended to encourage a healthier approach to body image within the fashion industry.
In her editor's letter, Alexandra Shulman, editor of British Vogue said: "As one of the fashion industry's most powerful voices, Vogue has a unique opportunity to engage with relevant issues where we feel we can make a difference."
Jonathan Newhouse, chairman of Vogue publisher Condé Nast International, said: "Vogue editors around the world want the magazines to reflect their commitment to the health of the models who appear on the pages and the well-being of their readers."